Preparation and comprehensive characterization of chitosan-based films enhanced with ferulic acid
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Nicolaus Copernicus University in Torun,
Faculty of Chemistry, Department of
Biomaterials and Cosmetic Chemistry,
Gagarin 7, 87-100 Torun, Poland
Submission date: 2024-08-25
Acceptance date: 2024-09-19
Publication date: 2024-09-23
Engineering of Biomaterials 2024;(172):08
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ABSTRACT
This study explores the development and detailed characterization of chitosan-based films enhanced with ferulic acid to improve their properties for biomedical, environmental, and packaging applications. Chitosan, a biopolymer derived from chitin, exhibits valuable attributes such as biocompatibility, biodegradability, and antimicrobial properties. However, it requires modifications to overcome limitations in mechanical strength, water permeability, and antioxidant properties. Ferulic acid, a phenolic compound, was incorporated into chitosan films at varying concentrations (1%, 2%, 5%, and 10%) to investigate its influence on film properties. The films were characterized through FTIR to confirm interactions between ferulic acid and chitosan, resulting in enhanced mechanical flexibility, thermal stability, and water resistance. Mechanical tests indicated that ferulic acid improved film flexibility while maintaining tensile strength, making it suitable for flexible packaging and wound dressings. Additionally, water vapour permeability and swelling tests suggested potential improvements in moisture control. Optical assessments showed increased whiteness and reduced colour variability, highlighting the aesthetic and protective advantages of ferulic acid-enriched films. These findings suggest that ferulic acid-modified chitosan films can serve as multifunctional biomaterials, addressing the growing demand for sustainable, high-performance materials in various industries. Further research on biological properties is recommended to fully establish their applicability in biomedicine and environmentally sensitive applications.